Relatively rare, autoimmune skin diseases occur when an organism become immunized against one of its own "constituents".
- Bullous pemphigoid: antibodies are directed specifically against skin cells. Although rare, erosive and ulcerative lesions can affect, in particular, the mucous membranes, the junctures of cutaneous tissue and mucus membranes and the skin.
- Non-Bullous pemphigoid: antibodies are directed against parts of any cell nucleus, especially those of the skin. Discoid lupus is a factor. This is the most common among autoimmune skin diseases. It affects only the face, symmetrically attacking the bridge of the nose, the periorbital regions and the ears.
- Symptoms: depigmentation, erythema, alopecia and crusts. Photosensitive disease.
- Treatment: long, using potent products with side effects.
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